Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1.

Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1.

The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM 240300), recessive AIRE mutations lead to autoimmunity targetting endocrine and other epithelial tissues, although chronic candidiasis usually appears first....

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Bibliographic Details
Main Authors: Anthony Meager, Kumuthini Visvalingam, Pärt Peterson, Kaidi Möll, Astrid Murumägi, Kai Krohn, Petra Eskelin, Jaakko Perheentupa, Eystein Husebye, Yoshihisa Kadota, Nick Willcox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1475653?pdf=render

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http://europepmc.org/articles/PMC1475653?pdf=render

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