Mechanisms controlling the effects of bevacizumab (avastin) on the inhibition of early but not late formed corneal neovascularization.

PURPOSE: To evaluate the effects and underlying mechanisms of early and late subconjunctival injection of bevacizumab on the inhibition of corneal neovascularization (NV). METHODS: Corneal NV was induced by closed eye contact lens wear followed by a silk suture tarsorrhaphy in rabbits. Weekly subcon...

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Bibliographic Details
Main Authors: Wei-Li Chen, Yan-Ming Chen, Hsiao-Sang Chu, Chung-Tien Lin, Lu-Ping Chow, Chih-Ta Chen, Fung-Rong Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979754?pdf=render