Inhibition of CSF1R and AKT by (±)-kusunokinin hinders breast cancer cell proliferation

Inhibition of CSF1R and AKT by (±)-kusunokinin hinders breast cancer cell proliferation

Kusunokinin, a lignan compound, inhibits cancer cell proliferation and induces apoptosis; however, the role of kusunokinin is not fully understood. Here, we aimed to identify a target protein of (−)-kusunokinin and determine the protein levels of its downstream molecules. We found that (−)-kusunokin...

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Bibliographic Details
Main Authors: Thidarath Rattanaburee, Varomyalin Tipmanee, Aman Tedasen, Tienthong Thongpanchang, Potchanapond Graidist
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Kusunokinin
Breast cancer
CSF1R
AKT
Cell proliferation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220305540

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220305540

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