Central administration of afzelin extracted from Ribes fasciculatum improves cognitive and memory function in a mouse model of dementia

Abstract Neurodegenerative disorders are characterized by the decline of cognitive function and the progressive loss of memory. The dysfunctions of the cognitive and memory system are closely related to the decreases in brain-derived neurotrophic factor (BDNF) and cAMP response element-binding prote...

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Bibliographic Details
Main Authors: So-Young Oh, Min Jun Jang, Yun-Hyeok Choi, Hongik Hwang, Hyewhon Rhim, Bonggi Lee, Chun Whan Choi, Min Soo Kim
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88463-6