Aberrant DNA Methylation of Two Tumor Suppressor Genes, p14ARF and p15INK4b, after Chronic Occupational Exposure to Low Level of Benzene

Aberrant DNA Methylation of Two Tumor Suppressor Genes, p14ARF and p15INK4b, after Chronic Occupational Exposure to Low Level of Benzene

Background: Exposure to benzene would be associated with many diseases including leukemia. Epigenetic alterations seem to be among the main mechanisms involved. Objective: To determine if chronic occupational exposure to low level of benzene would be associated with DNA methylation. Methods: Globa...

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Bibliographic Details
Main Authors: Iraj Jamebozorgi, Tayebeh Majidizadeh, Gholamreza Pouryagoub, Frouzandeh Mahjoubi
Format: Article
Language:English
Published: National Iranian Oil Company (NIOC) Health Organization 2018-07-01
Series:The International Journal of Occupational and Environmental Medicine
Subjects:
Benzene
DNA methylation
Genes, tumor suppressor
Tumor suppressor protein p14ARF
Cyclin-dependent kinase inhibitor p15
Neoplasms
Online Access:http://www.theijoem.com/ijoem/index.php/ijoem/article/view/1317

Internet

http://www.theijoem.com/ijoem/index.php/ijoem/article/view/1317

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