<i>Eleutherococcus sessiliflorus</i> Inhibits Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL)-Induced Osteoclast Differentiation and Prevents Ovariectomy (OVX)-Induced Bone Loss

<i>Eleutherococcus sessiliflorus</i> Inhibits Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL)-Induced Osteoclast Differentiation and Prevents Ovariectomy (OVX)-Induced Bone Loss

The aim of this study was to evaluate the effects of root bark of <i>Eleutherococcus sessiliflorus</i> (ES) on osteoclast differentiation and function in vitro and in vivo. In vitro, we found that ES significantly inhibited the RANKL-induced formation of TRAP-positive multinucleated oste...

Full description

Bibliographic Details
Main Authors: Sang-Yong Han, June-Hyun Kim, Eun-Heui Jo, Yun-Kyung Kim
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
<i>Eleutherococcus sessiliflorus</i>
Osteoporosis
RANKL
Osteoclast differentiation
NFATc1
c-Fos
Online Access:https://www.mdpi.com/1420-3049/26/7/1886

Internet

https://www.mdpi.com/1420-3049/26/7/1886

Similar Items