Viscous Core Liposomes Increase siRNA Encapsulation and Provides Gene Inhibition When Slightly Positively Charged

Viscous Core Liposomes Increase siRNA Encapsulation and Provides Gene Inhibition When Slightly Positively Charged

Since its discovery, evidence that siRNA was able to act as an RNA interference effector, led to its acceptation as a novel medicine. The siRNA approach is very effective, due to its catalytic mechanism, but still the limitations of its cellular delivery should be addressed. One promising form of no...

Full description

Bibliographic Details
Main Authors: Shayan Ahmed, Hugo Salmon, Nicholas Distasio, Hai Doan Do, Daniel Scherman, Khair Alhareth, Maryam Tabrizian, Nathalie Mignet
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
siRNA
neutral viscous core liposomes
positively charged viscous core liposomes
microfluidic device
3D cell cultures
encapsulation efficiency
Online Access:https://www.mdpi.com/1999-4923/13/4/479

Internet

https://www.mdpi.com/1999-4923/13/4/479

Similar Items