Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells

Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells

Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in...

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Bibliographic Details
Main Authors: Ying Liu, Eugenia G. Giannopoulou, Duancheng Wen, Ilaria Falciatori, Olivier Elemento, C. David Allis, Shahin Rafii, Marco Seandel
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11275

Internet

https://doi.org/10.1038/ncomms11275

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