Immune cell responses to amyloid-beta proteins: What is the extent and implications of amyloid-beta induced cytotoxicity in microglial cells and peripheral blood mononuclear cells?

Alzheimer’s disease (AD) is a neurodegenerative disease with cognitive and physical symptoms. Scientists generally accept the amyloid cascade hypothesis as the defining focus of AD pathology. Past studies have indicated that Aβ oligomers induced cytotoxicity in immune cells, but the role of Aβ monom...

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Bibliographic Details
Main Author: Cao, A.
Format: Article
Language:English
Published: Royal St. George's College 2017-07-01
Series:The Young Researcher
Subjects:
Online Access:http://www.theyoungresearcher.com/papers/cao.pdf