Analysis of the Antigenic and Prophylactic Properties of the Leishmania Translation Initiation Factors eIF2 and eIF2B in Natural and Experimental Leishmaniasis

Analysis of the Antigenic and Prophylactic Properties of the Leishmania Translation Initiation Factors eIF2 and eIF2B in Natural and Experimental Leishmaniasis

Different members of intracellular protein families are recognized by the immune system of the vertebrate host infected by parasites of the genus Leishmania. Here, we have analyzed the antigenic and immunogenic properties of the Leishmania eIF2 and eIF2B translation initiation factors. An in silico...

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Bibliographic Details
Main Authors: Esther Garde, Laura Ramírez, Laura Corvo, José C. Solana, M. Elena Martín, Víctor M. González, Carlos Gómez-Nieto, Aldina Barral, Manoel Barral-Netto, José M. Requena, Salvador Iborra, Manuel Soto
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Leishmania
antigens
interleukin-10
visceral leishmaniasis
translation initiation factors
experimental murine models
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00112/full

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http://journal.frontiersin.org/article/10.3389/fcimb.2018.00112/full

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