Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae

Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae

HIV-1 sexual transmission occurs mainly via mucosal semen exposures. In the female reproductive tract (FRT), seminal plasma (SP) induces physiological modifications, including inflammation. An effective HIV-1 vaccine should elicit mucosal immunity, however, modifications of vaccine responses by the...

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Bibliographic Details
Main Authors: Romain Marlin, Marie-Thérèse Nugeyre, Nicolas Tchitchek, Matteo Parenti, Cécile Lefebvre, Hakim Hocini, Fahd Benjelloun, Claude Cannou, Silvia Nozza, Nathalie Dereuddre-Bosquet, Yves Levy, Françoise Barré-Sinoussi, Gabriella Scarlatti, Roger Le Grand, Elisabeth Menu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
female reproductive tract (FRT)
seminal plasma
vaccine
mucosa
HIV-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00430/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00430/full

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