Changes in morphology, gene expression and protein content in chondrocytes cultured on a random positioning machine.

Tissue engineering of chondrocytes on a Random Positioning Machine (RPM) is a new strategy for cartilage regeneration. Using a three-dimensional RPM, a device designed to simulate microgravity on Earth, we investigated the early effects of RPM exposure on human chondrocytes of six different donors a...

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Bibliographic Details
Main Authors: Ganna Aleshcheva, Jayashree Sahana, Xiao Ma, Jens Hauslage, Ruth Hemmersbach, Marcel Egli, Manfred Infanger, Johann Bauer, Daniela Grimm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823937?pdf=render