Hypochlorous acid-mediated generation of glycerophosphocholine from unsaturated plasmalogen glycerophosphocholine lipids

Hypochlorous acid-mediated generation of glycerophosphocholine from unsaturated plasmalogen glycerophosphocholine lipids

The myeloperoxidase-derived metabolite hypochlorous acid (HOCl) promotes the selective cleavage of plasmalogens into chloro fatty aldehydes and 1-lysophosphatidylcholine (LPC). The subsequent conversion of the initially generated LPC was investigated in plasmalogen samples in dependence on the fatty...

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Bibliographic Details
Main Authors: Jacqueline Leßig, Jürgen Schiller, Jürgen Arnhold, Beate Fuchs
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Journal of Lipid Research
Subjects:
31P nuclear magnetic resonance
matrix-assisted laser desorption and ionization time-of-flight mass spectrometry
lysophosphatidylcholine
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425593

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http://www.sciencedirect.com/science/article/pii/S0022227520425593

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