A new sex-specific underlying mechanism for female schizophrenia: accelerated skewed X chromosome inactivation

A new sex-specific underlying mechanism for female schizophrenia: accelerated skewed X chromosome inactivation

Abstract Background X chromosome inactivation (XCI) is the mechanism by which the X-linked gene dosage is adjusted between the sexes. Evidence shows that many sex-specific diseases have their basis in X chromosome biology. While female schizophrenia patients often have a delayed age of disease onset...

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Bibliographic Details
Main Authors: Xinzhu Zhang, Yuhong Li, Lei Ma, Guofu Zhang, Min Liu, Chuanyue Wang, Yi Zheng, Rena Li
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Biology of Sex Differences
Subjects:
X chromosome inactivation
Schizophrenia
Onset age
PANSS
Skewing
Online Access:http://link.springer.com/article/10.1186/s13293-020-00315-6

Internet

http://link.springer.com/article/10.1186/s13293-020-00315-6

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