Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease
<p>Abstract</p> <p>Background</p> <p>Huntington's disease (HD) is an inherited neurogenerative disease caused by an abnormal expansion of glutamine repeats in the huntingtin protein. There is currently no treatment to prevent the neurodegeneration caused by this de...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-10-01
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| Series: | Molecular Brain |
| Online Access: | http://www.molecularbrain.com/content/2/1/33 |