Mannan-binding lectin inhibits Candida albicans-induced cellular responses in PMA-activated THP-1 cells through Toll-like receptor 2 and Toll-like receptor 4.

Mannan-binding lectin inhibits Candida albicans-induced cellular responses in PMA-activated THP-1 cells through Toll-like receptor 2 and Toll-like receptor 4.

BACKGROUND:Candida albicans (C. albicans), the most common human fungal pathogen, can cause fatal systemic infections under certain circumstances. Mannan-binding lectin (MBL),a member of the collectin family in the C-type lectin superfamily, is an important serum component associated with innate imm...

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Bibliographic Details
Main Authors: Mingyong Wang, Fanping Wang, Jianbin Yang, Dongfang Zhao, Hongpo Wang, Feng Shao, Wenjun Wang, Ruili Sun, Mingzhi Ling, Jingjing Zhai, Shijun Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877063?pdf=render

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http://europepmc.org/articles/PMC3877063?pdf=render

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