Disappearance of GFP-positive hepatocytes transplanted into the liver of syngeneic wild-type rats pretreated with retrorsine.

BACKGROUND AND AIM: Green fluorescent protein (GFP) is a widely used molecular tag to trace transplanted cells in rodent liver injury models. The differing results from various previously reported studies using GFP could be attributed to the immunogenicity of GFP. METHODS: Hepatocytes were obtained...

Full description

Bibliographic Details
Main Authors: Hiromichi Maeda, Masatoshi Shigoka, Yongchun Wang, Yingxin Fu, Russell N Wesson, Qing Lin, Robert A Montgomery, Hideaki Enzan, Zhaoli Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4010421?pdf=render