ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

Bacillus subtilis ParB forms multimeric networks involving non-specific DNA binding leading to DNA condensation. Previously, we found that an excess of the free C-terminal domain (CTD) of ParB impeded DNA condensation or promoted decondensation of pre-assembled networks (Fisher et al., 2017). Howeve...

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Bibliographic Details
Main Authors: Julene Madariaga-Marcos, Cesar L Pastrana, Gemma LM Fisher, Mark Simon Dillingham, Fernando Moreno-Herrero
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-03-01
Series:eLife
Subjects:
ParB
single molecule
magnetic tweezers
TIRF microscopy
bacterial chromosome dynamics
Spo0J
Online Access:https://elifesciences.org/articles/43812

Internet

https://elifesciences.org/articles/43812

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