The potential for isotope dilution-LC-MS/MS to improve laboratory measurement of C-peptide: Reasons and critical determinants

The potential for isotope dilution-LC-MS/MS to improve laboratory measurement of C-peptide: Reasons and critical determinants

Human C-peptide is secreted in equimolar amounts with insulin by pancreatic beta-cells. Measurement of C-peptide plays an important role in the diagnosis and treatment of diabetes where it is used to evaluate the function of islet cells. However, C-peptide measurement results across different labora...

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Bibliographic Details
Main Authors: Yuhang Deng, Haijian Zhao, Qingxiang Liu, Weiyan Zhou, Chuanbao Zhang
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
Isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)
C-peptide
Standardization
Sample preparation
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X21000122

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http://www.sciencedirect.com/science/article/pii/S2667145X21000122

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