Characterization of microminipig as a laboratory animal for pharmacological study by analyzing bepridil-induced cardiovascular responses

Since microminipig is becoming attractive model for various cardiac electropharmacological applications, which may meet consideration of 3Rs. We characterized microminipigs by analyzing how multi-ionic channel inhibitor bepridil may affect their in situ hearts in comparison with dogs. Bepridil in do...

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Bibliographic Details
Main Authors: Yoshio Nunoi, Mihoko Hagiwara-Nagasawa, Ryuichi Kambayashi, Ai Goto, Koki Chiba, Takeshi Wada, Hiroko Izumi-Nakaseko, Akio Matsumoto, Yoshinori Watanabe, Atsushi Sugiyama
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320300116