Probing the Kinetic and Thermodynamic Fingerprints of Anti-EGF Nanobodies by Surface Plasmon Resonance

Probing the Kinetic and Thermodynamic Fingerprints of Anti-EGF Nanobodies by Surface Plasmon Resonance

Despite the widespread use of antibodies in clinical applications, the precise molecular mechanisms underlying antibody–antigen (Ab–Ag) interactions are often poorly understood. In this study, we exploit the technical features of a typical surface plasmon resonance (SPR) biosensor to dissect the kin...

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Bibliographic Details
Main Authors: Salvador Guardiola, Monica Varese, Marta Taulés, Mireia Díaz-Lobo, Jesús García, Ernest Giralt
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceuticals
Subjects:
nanobodies
SPR
biophysics
thermodynamics
molecular recognition
EGF
Online Access:https://www.mdpi.com/1424-8247/13/6/134

Internet

https://www.mdpi.com/1424-8247/13/6/134

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