SULF2 methylation is associated with in vitro cisplatin sensitivity and clinical efficacy for gastric cancer patients treated with a modified FOLFOX regimen.

SULF2 methylation is associated with in vitro cisplatin sensitivity and clinical efficacy for gastric cancer patients treated with a modified FOLFOX regimen.

OBJECTIVE: Biomarkers capable of discriminating the patients who are likely to respond to certain chemotherapeutic agents could improve the clinical efficiency. The sulfatases(SULFs) play a critical role in the pathogenesis of a variety of human cancers. Here, we focused our investigation on the pro...

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Bibliographic Details
Main Authors: Jie Shen, Jia Wei, Hao Wang, Yang Yang, Guofeng Yue, Lin Wang, Lixia Yu, Li Xie, Xia Sun, Xinyu Bian, Zhengyun Zou, Xiaoping Qian, Wenxian Guan, Baorui Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790846?pdf=render

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http://europepmc.org/articles/PMC3790846?pdf=render

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