Role of oxidative and nitrosative stress in pathophysiology of toxic epidermal necrolysis and Stevens Johnson syndrome-A pilot study

Background: Oxidative and nitrosative stress caused by drug metabolism may be a trigger for keratinocyte apoptosis in the epidermis seen in toxic epidermal necrolysis (TEN) and Stevens Johnson syndrome (SJS). Aims: To estimate oxidative damage in the serum and to examine the role of nitric oxide in...

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Bibliographic Details
Main Authors: Dincy Peter, G Jayakumar Amirtharaj, Teena Mathew, Susanne Pulimood, Anup Ramachandran
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Indian Journal of Dermatology
Subjects:
Online Access:http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=5;spage=427;epage=431;aulast=Peter