Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes

Ribosome profiling suggests that ribosomes occupy many regions of the transcriptome thought to be noncoding, including 5′ UTRs and long noncoding RNAs (lncRNAs). Apparent ribosome footprints outside of protein-coding regions raise the possibility of artifacts unrelated to translation, particularly...

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Bibliographic Details
Main Authors: Nicholas T. Ingolia, Gloria A. Brar, Noam Stern-Ginossar, Michael S. Harris, Gaëlle J.S. Talhouarne, Sarah E. Jackson, Mark R. Wills, Jonathan S. Weissman
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714006299