The Good, the Bad and the Unknown of CD38 in the Metabolic Microenvironment and Immune Cell Functionality of Solid Tumors

The regulation of the immune microenvironment within solid tumors has received increasing attention with the development and clinical success of immune checkpoint blockade therapies, such as those that target the PD-1/PD-L1 axis. The metabolic microenvironment within solid tumors has proven to be an...

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Bibliographic Details
Main Authors: Jessica M. Konen, Jared J. Fradette, Don L. Gibbons
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/1/52