ERCC1 Is a Predictor of Anthracycline Resistance and Taxane Sensitivity in Early Stage or Locally Advanced Breast Cancers

Genomic instability could be a beneficial predictor for anthracycline or taxane chemotherapy. We interrogated 188 DNA repair genes in the METABRIC cohort (<i>n</i> = 1980) to identify genes that influence overall survival (OS). We then evaluated the clinicopathological significance of ER...

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Bibliographic Details
Main Authors: Tarek M. A. Abdel-Fatah, Reem Ali, Maaz Sadiq, Paul M. Moseley, Katia A. Mesquita, Graham Ball, Andrew R. Green, Emad A. Rakha, Stephen Y. T. Chan, Srinivasan Madhusudan
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/8/1149