A systems biology approach towards the identification of candidate therapeutic genes and potential biomarkers for Parkinson's disease.

Parkinson's disease (PD) is an irreversible and incurable multigenic neurodegenerative disorder. It involves progressive loss of mid brain dopaminergic neurons in the substantia nigra pars compacta (SN). We compared brain gene expression profiles with those from the peripheral blood cells of a...

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Bibliographic Details
Main Authors: Meena Kishore Sakharkar, Sarinder Kaur Kashmir Singh, Karthic Rajamanickam, Musthafa Mohamed Essa, Jian Yang, Saravana Babu Chidambaram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220995