Modulation of formin processivity by profilin and mechanical tension

Modulation of formin processivity by profilin and mechanical tension

Formins are major regulators of actin networks. They enhance actin filament dynamics by remaining processively bound to filament barbed ends. How biochemical and mechanical factors affect formin processivity are open questions. Monitoring individual actin filaments in a microfluidic flow, we report...

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Bibliographic Details
Main Authors: Luyan Cao, Mikael Kerleau, Emiko L. Suzuki, Hugo Wioland, Sandy Jouet, Berengere Guichard, Martin Lenz, Guillaume Romet-Lemonne, Antoine Jegou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
actin
cytoskeleton
microfluidics
mechanotransduction
formin
profilin
Online Access:https://elifesciences.org/articles/34176

Internet

https://elifesciences.org/articles/34176

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