Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium

Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium

Compartmentalization of diverse types of signaling molecules contributes to the precise coordination of signal propagation. The primary cilium fulfills this function by acting as a spatiotemporally confined sensory signaling platform. For the integrity of ciliary signaling, it is mandatory that the...

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Bibliographic Details
Main Authors: Philipp Tschaikner, Florian Enzler, Omar Torres-Quesada, Pia Aanstad, Eduard Stefan
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
kinase
anchoring proteins
akap
orphan gpcr
signalosome
second messenger
camp
adenylyl cyclase
hedgehog signaling
molecular interactions
dynamic complexes
signaling nodes
signaling circuits
compartmentalization
Online Access:https://www.mdpi.com/2073-4409/9/1/118

Internet

https://www.mdpi.com/2073-4409/9/1/118

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