Lgr4 in Ocular Development and Glaucoma

The leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4, also called GPR48) plays a key role in multiple developmental processes, and mice lacking Lgr4 display anterior segment dysgenesis leading to early-onset glaucomatous retinal ganglion cell loss as well as defective eyelid formati...

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Bibliographic Details
Main Authors: Stefan Siwko, Li Lai, Jinsheng Weng, Mingyao Liu
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2013/987494