Lgr4 in Ocular Development and Glaucoma
The leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4, also called GPR48) plays a key role in multiple developmental processes, and mice lacking Lgr4 display anterior segment dysgenesis leading to early-onset glaucomatous retinal ganglion cell loss as well as defective eyelid formati...
Main Authors: | Stefan Siwko, Li Lai, Jinsheng Weng, Mingyao Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
|
Series: | Journal of Ophthalmology |
Online Access: | http://dx.doi.org/10.1155/2013/987494 |
Similar Items
-
LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation
by: Yu Wang, et al.
Published: (2020-05-01) -
LGR4 and LGR5 regulate hair cell differentiation in the sensory epithelium of the developing mouse cochlea.
by: Magdalena Zak, et al.
Published: (2016-08-01) -
LGR4 and LGR5 Function Redundantly During Human Endoderm DifferentiationSummary
by: Yu-Hwai Tsai, et al.
Published: (2016-09-01) -
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.
by: Heinz Ruffner, et al.
Published: (2012-01-01) -
Förvaltningsförändring och läroplaner : En idéanalys av Lgr 69, Lgr 80, Lpo 94 samt Lgr 11
by: Nilsson Åsman, Thea
Published: (2021)