Integrated sequence-structure motifs suffice to identify microRNA precursors.

BACKGROUND: Upwards of 1200 miRNA loci have hitherto been annotated in the human genome. The specific features defining a miRNA precursor and deciding its recognition and subsequent processing are not yet exhaustively described and miRNA loci can thus not be computationally identified with sufficien...

Full description

Bibliographic Details
Main Authors: Xiuqin Liu, Shunmin He, Geir Skogerbø, Fuzhou Gong, Runsheng Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3305290?pdf=render