Localization of ανβ6 integrin-TGF-β1/Smad3, mTOR and PPARγ in experimental colorectal fibrosis

A simultaneous action of several pro-fibrotic mediators appears relevant in the development of fibrosis. There are evidences that transforming growth factor-β (TGF-β)/Smad3 pathway forms with αvβ6 integrin, mammalian target of Rapamycin (mTOR) and peroxisome proliferator-activated receptor-γ (PPARγ)...

Full description

Bibliographic Details
Main Authors: G. Latella, A. Vetuschi, R. Sferra, S. Speca, E. Gaudio
Format: Article
Language:English
Published: PAGEPress Publications 2013-12-01
Series:European Journal of Histochemistry
Subjects:
Online Access:http://www.ejh.it/index.php/ejh/article/view/2237