Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding

Export of Plasmodium falciparum proteins into infected erythrocytes relies upon the PEXEL motif in target proteins. Here Boddey et al.challenge the hypothesis that the PEXEL motif mediates export by binding PI(3)P and instead suggest it acts via cleavage by plasmepsin V.

Bibliographic Details
Main Authors:	Justin A. Boddey, Matthew T. O’Neill, Sash Lopaticki, Teresa G. Carvalho, Anthony N. Hodder, Thomas Nebl, Stephan Wawra, Pieter van West, Zeinab Ebrahimzadeh, Dave Richard, Sven Flemming, Tobias Spielmann, Jude Przyborski, Jeff J. Babon, Alan F. Cowman
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-02-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms10470

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https://doi.org/10.1038/ncomms10470

Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding

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