Chiral Separations in Preparative Scale: A Medicinal Chemistry Point of View

Enantiomeric separation is a key step in the development of a new chiral drug. Preparative liquid chromatography (LC) continues to be the technique of choice either during the drug discovery process, to achieve a few milligrams, or to a scale-up during the clinical trial, needing kilograms of materi...

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Bibliographic Details
Main Authors: Madalena M.M. Pinto, Carla Fernandes, Maria E. Tiritan
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/8/1931