A Versatile Macromer-Based Glycosaminoglycan (sHA3) Decorated Biomaterial for Pro-Osteogenic Scavenging of Wnt Antagonists

A Versatile Macromer-Based Glycosaminoglycan (sHA3) Decorated Biomaterial for Pro-Osteogenic Scavenging of Wnt Antagonists

High serum levels of Wnt antagonists are known to be involved in delayed bone defect healing. Pharmaceutically active implant materials that can modulate the micromilieu of bone defects with regard to Wnt antagonists are therefore considered promising to support defect regeneration. In this study, w...

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Bibliographic Details
Main Authors: Mathis Gronbach, Franziska Mitrach, Stephanie Möller, Sandra Rother, Sabrina Friebe, Stefan G. Mayr, Matthias Schnabelrauch, Vera Hintze, Michael C. Hacker, Michaela Schulz-Siegmund
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
hyaluronan
sclerostin
DKK1
surface modification
tissue engineering
scavenging
Online Access:https://www.mdpi.com/1999-4923/12/11/1037

Internet

https://www.mdpi.com/1999-4923/12/11/1037

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