Interaction between Red Meat Intake and NAT2 Genotype in Increasing the Risk of Colorectal Cancer in Japanese and African Americans.

Interaction between Red Meat Intake and NAT2 Genotype in Increasing the Risk of Colorectal Cancer in Japanese and African Americans.

Heterocyclic aromatic amines formed in cooked meat may be an underlying mechanism for the red meat-colorectal cancer (CRC) association. These compounds require bioactivaction by N-acetyltransferase 2 (NAT2). An interaction effect between red meat consumption and NAT2 in increasing CRC risk has been...

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Bibliographic Details
Main Authors: Hansong Wang, Motoki Iwasaki, Christopher A Haiman, Suminori Kono, Lynne R Wilkens, Temitope O Keku, Sonja I Berndt, Shoichiro Tsugane, Loïc Le Marchand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4684304?pdf=render

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http://europepmc.org/articles/PMC4684304?pdf=render

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