A genome-wide survey of mutations in the Jurkat cell line
Abstract Background The Jurkat cell line has an extensive history as a model of T cell signaling. But at the turn of the 21st century, some expression irregularities were observed, raising doubts about how closely the cell line paralleled normal human T cells. While numerous expression deficiencies...
Main Authors: | Louis Gioia, Azeem Siddique, Steven R. Head, Daniel R. Salomon, Andrew I. Su |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-018-4718-6 |
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