A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition

As heparan sulfate proteoglycans (HSPGs) are known as co-receptors to interact with numerous growth factors and then modulate downstream biological activities, overexpression of HS/HSPG on cell surface acts as an increasingly reliable prognostic factor in tumor progression. Cell penetrating peptides...

Full description

Bibliographic Details
Main Authors: Chien-Jung Chen, Kang-Chiao Tsai, Ping-Hsueh Kuo, Pei-Lin Chang, Wen-Ching Wang, Yung-Jen Chuang, Margaret Dah-Tsyr Chang
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/237969