Risk of Atypical HUS Among Family Members of Patients Carrying Complement Regulatory Gene Abnormality

Risk of Atypical HUS Among Family Members of Patients Carrying Complement Regulatory Gene Abnormality

Introduction: Atypical hemolytic uremic syndrome (aHUS) is mainly due to complement regulatory gene abnormalities with a dominant pattern but incomplete penetrance. Thus, healthy carriers can be identified in any family of aHUS patients, but it is unpredictable if they will eventually develop aHUS....

Full description

Bibliographic Details
Main Authors: Gianluigi Ardissino, Selena Longhi, Luigi Porcaro, Giulia Pintarelli, Bice Strumbo, Valentina Capone, Donata Cresseri, Giulia Loffredo, Francesca Tel, Stefania Salardi, Martina Sgarbanti, Laura Martelli, Evangeline Millicent Rodrigues, Nicolò Borsa-Ghiringhelli, Giovanni Montini, Manuela Seia, Massimo Cugno, Fabio Carfagna, Dario Consonni, Silvana Tedeschi
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Kidney International Reports
Subjects:
aHUS
complement genes
penetrance
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024921010330

Internet

http://www.sciencedirect.com/science/article/pii/S2468024921010330

Similar Items