Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes

Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes

<p>Abstract</p> <p>Background</p> <p>The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex o...

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Bibliographic Details
Main Authors: Sárvári Miklós, Hrabovszky Erik, Kalló Imre, Solymosi Norbert, Likó István, Berchtold Nicole, Cotman Carl, Liposits Zsolt
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Journal of Neuroinflammation
Subjects:
Frontal cortex
Rat
Ovarian hormones
Expression analysis
Microglia activation
Postmenopausal women
Online Access:http://www.jneuroinflammation.com/content/9/1/264

Internet

http://www.jneuroinflammation.com/content/9/1/264

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