Global MicroRNA Profiling Uncovers miR-206 as a Negative Regulator of Hematopoietic Commitment in Human Pluripotent Stem Cells

Global MicroRNA Profiling Uncovers miR-206 as a Negative Regulator of Hematopoietic Commitment in Human Pluripotent Stem Cells

Although human pluripotent stem cells (hPSCs) can theoretically differentiate into any cell type, their ability to produce hematopoietic cells is highly variable from one cell line to another. The underlying mechanisms of this heterogeneity are not clearly understood. Here, using a whole miRNome ana...

Full description

Bibliographic Details
Main Authors: Stéphane Flamant, Jean-Claude Chomel, Christophe Desterke, Olivier Féraud, Emilie Gobbo, Maria-Teresa Mitjavila-Garcia, Adlen Foudi, Frank Griscelli, Ali G. Turhan, Annelise Bennaceur-Griscelli
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
Human pluripotent stem cells
embryonic stem cells
induced pluripotent stem cells
hematopoietic potential
microRNAs
miR-206
Online Access:https://www.mdpi.com/1422-0067/20/7/1737

Internet

https://www.mdpi.com/1422-0067/20/7/1737

Similar Items