The Impact of Hypoxia on Neutrophil Degranulation and Consequences for the Host

Neutrophils are key effector cells of innate immunity, rapidly recruited to defend the host against invading pathogens. Neutrophils may kill pathogens intracellularly, following phagocytosis, or extracellularly, by degranulation and the release of neutrophil extracellular traps; all of these microbi...

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Bibliographic Details
Main Authors: Katharine M. Lodge, Andrew S. Cowburn, Wei Li, Alison M. Condliffe
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/4/1183