A genetic epilepsy rat model displays endophenotypes of psychosis

A genetic epilepsy rat model displays endophenotypes of psychosis

The incidence of psychosis is increased in people with epilepsy, including idiopathic generalized epilepsies. To study the biological basis for this co-morbidity, we compared GAERS, a genetic rat model of absence epilepsy, to non-epileptic control rats (NEC). Mature, 14-week old GAERS showed enhance...

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Bibliographic Details
Main Authors: Nigel C. Jones, Sally Martin, Ika Megatia, Tahir Hakami, Michael R. Salzberg, Didier Pinault, Margaret J. Morris, Terence J. O'Brien, Maarten van den Buuse
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Neurobiology of Disease
Subjects:
GAERS
Stimulant-induced hyperlocomotor activity
Prepulse inhibition
Gamma power
Dopamine transporter
Dopamine receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110000392

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http://www.sciencedirect.com/science/article/pii/S0969996110000392

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