Adjunctive use of physostigmine salicylate (Anticholium®) in perioperative sepsis and septic shock: study protocol for a randomized, double-blind, placebo-controlled, monocentric trial (Anticholium® per Se)

Adjunctive use of physostigmine salicylate (Anticholium®) in perioperative sepsis and septic shock: study protocol for a randomized, double-blind, placebo-controlled, monocentric trial (Anticholium® per Se)

Abstract Background Severe sepsis and septic shock remain a major challenge, even in modern intensive care. In Germany, about 68,000 patients die annually because of septic diseases, characterized by a complex systemic inflammatory response. Causal treatment of the underlying infection is essential...

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Bibliographic Details
Main Authors: Johannes B. Zimmermann, Nadine Pinder, Thomas Bruckner, Monika Lehmann, Johann Motsch, Thorsten Brenner, Torsten Hoppe-Tichy, Stefanie Swoboda, Markus A. Weigand, Stefan Hofer
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Trials
Subjects:
Physostigma venenosum
Antilirium
Cholinesterase inhibitor
Continuous administration
Eserine
Eseroline
Online Access:http://link.springer.com/article/10.1186/s13063-017-2231-x

Internet

http://link.springer.com/article/10.1186/s13063-017-2231-x

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