Molecular Modeling of Prion Transmission to Humans

Molecular Modeling of Prion Transmission to Humans

Using different prion strains, such as the variant Creutzfeldt-Jakob disease agent and the atypical bovine spongiform encephalopathy agents, and using transgenic mice expressing human or bovine prion protein, we assessed the reliability of protein misfolding cyclic amplification (PMCA) to model int...

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Bibliographic Details
Main Authors: Etienne Levavasseur, Nicolas Privat, Juan-Carlos Espinosa Martin, Steve Simoneau, Thierry Baron, Benoit Flan, Juan-Maria Torres, Stéphane Haïk
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Viruses
Subjects:
Prion
Protein misfolding cyclic amplification
molecular model
interspecies barrier
Online Access:http://www.mdpi.com/1999-4915/6/10/3766

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http://www.mdpi.com/1999-4915/6/10/3766

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