Filarial excretory-secretory products induce human monocytes to produce lymphangiogenic mediators.

The nematodes Wuchereria bancrofti and Brugia spp. infect over 120 million people worldwide, causing lymphedema, elephantiasis and hydrocele, collectively known as lymphatic filariasis. Most infected individuals appear to be asymptomatic, but many exhibit sub-clinical manifestations including the ly...

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Bibliographic Details
Main Authors: Tiffany Weinkopff, Charles Mackenzie, Rob Eversole, Patrick J Lammie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4091784?pdf=render