Early Treatment with Intranasal Neostigmine Reduces Mortality in a Mouse Model of Naja naja (Indian Cobra) Envenomation

Objective. Most snakebite deaths occur prior to hospital arrival; yet inexpensive, effective, and easy to administer out-of-hospital treatments do not exist. Acetylcholinesterase inhibitors can be therapeutic in neurotoxic envenomations when administered intravenously, but nasally delivered drugs co...

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Bibliographic Details
Main Authors: Matthew R. Lewin, Stephen P. Samuel, David S. Wexler, Philip Bickler, Sakthivel Vaiyapuri, Brett D. Mensh
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2014/131835