Evolution of BRET biosensors from live cell to tissue-scale in vivo imaging

Development of bioluminescence resonance energy transfer [BRET] based genetic sensors for sensing biological functions such as protein-protein interactions [PPIs] in vivo has a special value in measuring such dynamic events at their native environment. Since its inception in the late nineties, BRET...

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Bibliographic Details
Main Authors: ABHIJIT eDE, Akshi eJasani, Rohit eArora, Sanjiv Sam Gambhir
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00131/full