Claudin11 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin, but Uncommon in Nevus Cell Nevi

Claudin11 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin, but Uncommon in Nevus Cell Nevi

Epigenetic inactivation of tumor-related genes is an important characteristic in the pathology of human cancers, including melanomagenesis. We analyzed the epigenetic inactivation of Claudin 11 (CLDN11) in malignant melanoma (MM) of the skin, including six melanoma cell lines, 39 primary melanoma, 4...

Full description

Bibliographic Details
Main Authors: Sara K. Walesch, Antje M. Richter, Peter Helmbold, Reinhard H. Dammann
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Cancers
Subjects:
malignant melanoma
Claudin 11
tumor suppressor gene
epigenetics
DNA methylation
Online Access:http://www.mdpi.com/2072-6694/7/3/0834

Internet

http://www.mdpi.com/2072-6694/7/3/0834

Similar Items